Adolf MayerAdolf Mayer:
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• Infectious sap from tobacco induce disease.
• Gave term Mosaikkrankheit for mosaic
Dmitri IvanovskyDmitri Ivanovsky:
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• Sap retained infectivity even after filtration through chamberland porcelain filter, doubted toxin produced by bacterium as cause.
M . W . BeijerinckM . W . Beijerinck:
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• In Netherland finally established the cause of tobacco mosaic disease and named the agent as “ Contagium vivum fluidum ” – gave the term Virus .
• Published paper “ Uber ein Contagium vivum fluidum als Ursache der Fleckenkrankheit der Tabaksblatter” ----- called Father of Plant Virology
Max KnollMax Knoll:
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• He was a German electrical engineer developed Electron Microscope along with EAF Ruska
Ernst RuskaErnst Ruska:
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• Invented Electron Microscope
W . M . StanleyW . M . Stanley:
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• Crystallized virus
Norman PirieNorman Pirie:
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• Reported that TMV contains nucleoprotein ( 5 % )
Frederick Charles Bawden Frederick Charles Bawden :
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• Reported that TMV contains nucleoprotein ( 5 % )
Helmut RuskaHelmut Ruska:
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• Were the first to observe TMV under electron microscope
A. GiererA. Gierer:
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• Showed that only nucleic acid of TMV is infective and protein coat does not have any role in infection .
G. Schramm G. Schramm:
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• Showed that only nucleic acid of TMV is infective and protein coat does not have any role in infection.
Basil Kassanis Basil Kassanis :
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• Coined the term Satellite virus , associated with TNV
Theodor Otto DienerTheodor Otto Diener :
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• Discovered PSTVd – Viroid
Stanley Benjamin Prusiner Stanley Benjamin Prusiner :
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• Discovered Prions in animals : Nobel Prize in 1997 in Medicines
Cesar MilsteinCésar Milstein:
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• “Hybridoma technology” in monoclonal antibodies production – Nobel prize in 1984
Niels Kaj Jerne, Kohler Niels Kaj Jerne, Köhler :
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• “Hybridoma technology” in monoclonal antibodies production – Nobel prize in 1984
Andrew FireAndrew Fire:
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• Awarded Nobel Prize for their work RNA interference – Gene silencing by dsRNA.
Craig C. MelloCraig C. Mello:
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• Awarded Nobel Prize for their work RNA interference – Gene silencing by dsRNA.
Paul Ahlquist Paul Ahlquist:
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• Infectious viral RNA transcribed in vitro from cDNA clones